The size and size distribution of low turbidity suspensions in various (bio)pharmaceutical products, including liposomes, lipid nanoparticles, recombinant proteins, and antibodies, plays a significant role in their pharmacokinetic and pharmacodynamic profile in vivo. These factors directly influence therapeutic efficacy, immunogenicity, and safety. Consequently, particle size is considered one of the critical quality attributes for such products.
Non-invasive, fast particle size characterization of concentrated flowing nanosuspensions is a cost-effective and efficient option to improve nanoparticle-based industrial and R&D processes.