Researchers with The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) have entered a federal cooperative agreement, valued up to $9.42 million, that will help them further develop Ohio State's biodosimetry technology to discover noninvasive biomarkers for radiation exposure – work that will have national security applications.
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COLUMBUS, Ohio - A new study of advanced small-cell lung cancer (SCLC) led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) has identified molecular patterns linked to patients developing resistance to certain therapies.
This study, published in the journal
JTO Clinical and Research Reports, examined more than 60 tumors from five patients. OSUCCC - James researchers identified distinct mutational and molecular changes in four SCLC subtypes. The findings provide new insights into the patterns treatment resistance and could offer new targets for the development of more effective immunotherapy and other therapies for advanced SCLC, which progresses quickly and is usually fatal.
Study suggests common drug could be used to prevent certain skin cancers ANI | Updated: Apr 14, 2021 19:09 IST
Washington [US], April 14 (ANI): A new research has suggested that an oral drug currently used in the clinical setting to treat neuromuscular diseases could also help prevent a common form of skincancer caused by damage from ultraviolet-B radiation from the sun.
The findings of the study were published in the journal Cancer Prevention Research .
The study was led by researchers at The Ohio State University Comprehensive Cancer Center Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC James).
While this data was gathered from preclinical studies, senior author Sujit Basu, MD, PhD, says preliminary results in animal models are very promising and worthy of immediate further investigation through phase I human studies.
Routine Drug may be Used to Prevent Few Skin Cancers by Angela Mohan on April 14, 2021 at 12:42 PM
Skin cancer could be treated by an oral drug currently used in the clinical setting to treat neuromuscular diseases, as per the data published by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James).
While this data was gathered from preclinical studies, senior author Sujit Basu, MD, PhD, says preliminary results in animal models are very promising and worthy of immediate further investigation through phase I human studies.
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