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Home School: Clinical Trials Went Virtual in COVID-19—Are They Here to Stay?

Lockdowns opened doors for RCTs without in-person contact. Time will tell whether they deliver on diversity and outcomes.

United statesMary mcdermottMary norine walshJames januzzi jrDavid cohenMd northwestern university feinberg school of medicineAmerican heart associationAmerican college of cardiologyDrug administrationHeart centerVincent heart centerBaim institute for clinical researchClinical trials centerCardiovascular research foundationMassachusetts general hospitalBaim institute

A Way to Funnel Patients From ER Discharge to Further Coronary Testing

A Way to Funnel Patients From ER Discharge to Further Coronary Testing
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United statesColl cardiolNicole louKavitha chinnaiyanJames januzzi jrJournal of the american college cardiologyBaim institute for clinical researchBeaumont health in royal oakAmerican collegeBeaumont healthRoyal oakJames januzziMassachusetts general hospitalBaim instituteClinical researchRoyal infirmary

Use of a Rapid, High-Sensitivity Troponin Protocol Doesn t Boost 1-Year Outcomes

There were more downstream tests and some hints of harm, although one expert cautions this may have been chance.

New yorkUnited statesFlinders universitySouth australiaDeepak bhattRoxana mehranJames januzzi jrAmerican college of cardiologyJournal of the american college cardiologyPhd flinders universityAmerican collegeRoche diagnosticsMassachusetts general hospitalBest managementIcahn schoolMount sinai

DARE-19 Didn t Pay Off for Farxiga in COVID-19

But trial may still show SGLT2 inhibitor is safe for sicker patients

North carolinaUnited statesDapagliflozin farxigaSanjeev gulatiMikhail kosiborodJames januzzi jrSaint luke mid america heart instituteAmerican college of cardiologySanger heart vascular institute in charlotteSaint lukeMid america heart instituteKansas cityAmerican collegeMassachusetts general hospitalSanger heartVascular institute

Dapagliflozin No Help, but No Harm, in Hospitalized COVID-19 Patients

Full trial results showed numerically lower event rates with the SGLT2 inhibitor and importantly no major signal of ketoacidosis.

District of columbiaUnited statesMikhail kosiborodJames januzziJames januzzi jrVascular instituteAmerican college of cardiologyMd saint luke mid america heart instituteSaint lukeMid america heart instituteKansas cityAmerican collegeMassachusetts general hospitalIoana baracMedstar heartமாவட்டம் ஆஃப் கொலம்பியா