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A randomized phase 3 study of parsaclisib plus ruxolitinib for adults with myelofibrosis appeared unlikely to meet its primary endpoint and will be discontinued, according to the agents’ manufacturer.The double-blind LIMBER-304 trial evaluated the safety and efficacy of parsaclisib (Incyte), a novel oral inhibitor of the phosphatidylinositol 3-kinase (PI3K) delta, in combination with the
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