regard to treatments. there aren t many patients with these trials. they use medications that are a type of muscle relaxant. it s really the legs that are starting to tremor significantly when someone is standing. so you can relax the muscles, they even use certain medications that are typically used to treat seizures, this isn t a seizure, but sometimes those medications can be helpful as well. we may be seeing this unfold realtime, brianna, in the sense that she may have noticed these symptoms herself, this is the typical age when someone gets diagnosed. she may be going through the evaluation process, trying out different medications and seeing what works. i should point out, unlike with parkinson s disease, this typically is not something that sort of ultimately leads to someone becoming increasingly disabled. it really is a tremor primarily when someone is standing still. that is very interesting. thank you so much. it s a stunning number.