Date Time
Stirring up Conflicts in Tumour Cells
With two commercially available inhibitors, the cell cycle of the cancer cells in the childhood tumour neuroblastoma can be disrupted at a key point causing tumour cell death.
Survival curve of the TH-MYCN mouse model during long-term treatment with Aurora-A inhibitor (purple), ATR inhibitor (blue) or the combination of both agents (red). It is clearly visible that the combination therapy prolongs survival time. (Image: Gabriele Büchel / Universität Würzburg)
Neuroblastomas are malignant solid tumours that occur mainly in early childhood. They arise from degenerated immature cells of the sympathetic nervous system.