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Benefits and Limitations Surrounding Current Treatment for PV

Data for Luspatercept Highlight Evolving Treatment Landscape in Lower-Risk MDS

Uwe Platzbecker, MD, discusses the FDA approval of luspatercept for the treatment of anemia in patients who have not had prior treatment with erythropoiesis-stimulating agent and may require regular red blood cell transfusions could change the sequencing of agents for this patient population.

Hematopoietic Cell Transplantation Potentially Curative for High-Risk Patients with MDS

Allogeneic HCT Improves Survival Rates for TP53-Mutated MDS

A recent study suggests that patients with myelodysplastic syndrome (MDS) could potentially benefit from allogeneic hematopoietic cell transplantation (HCT) regardless of genetic mutation status.

FDA Approves Luspatercept for First-line Treatment of Anemia in Lower-Risk MDS

The FDA has approved luspatercept-aamt (Reblozyl) for the treatment of anemia without prior erythropoiesis stimulating agent (ESA) use in adult patients with very low– to intermediate-risk myelodysplastic syndrome (MDS) who may require regular red blood cell (RBC) transfusions.

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