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FDA Approves Merck s KEYTRUDA® (pembrolizumab) Plus Chemoradiotherapy as Treatment for Patients With FIGO 2014 Stage III-IVA Cervical Cancer -January 12, 2024 at 05:31 pm EST

KEYTRUDA is the first and only anti-PD-1 therapy approved in combination with chemoradiotherapy for these patients Approval marks third FDA-approved indication for KEYTRUDA in cervical cancer and.

United statesGursel aktanMerck co incEuropean network for gynaecological oncological trialPatient support programMerck access programMerck patient support programStatement of merck co incUniversity of arizona college medicineInternational federation of gynecologyFoundation incMerck research laboratoriesExchange commissionDrug administrationCreighton university school of medicineInternational federation

Procedural sedation and analgesia versus general anesthesia for hysteroscopic myomectomy (PROSECCO trial): A multicenter randomized controlled trial

Julia van der Meulen and co-workers compare procedural sedation and analgesia versus general anesthesia in women undergoing hysteroscopic myomectomy for fibroids.

United statesNoord brabantUnited kingdomEteläuomen läiJennye myersGynaecologie nederlandAmerican society of anesthesiologistsResearch in obstetricsCentre in veldhovenDutch gynecologic patient organizationHealth researchInternational federation of gynecologyUniversity of manchesterDutch consortium for healthcare evaluationDevelopment zonAmerican society

Genomic instability analysis in DNA from Papanicolaou test provides proof-of-principle early diagnosis of high-grade serous ovarian cancer

Genomic instability analysis in DNA from Papanicolaou test provides proof-of-principle early diagnosis of high-grade serous ovarian cancer
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International federation of gynecologyReporting recommendationsTumor marker prognostic studiesBecause papInternational federationGenomic identificationSignificant targetsCancer genome atlas ovarian

FDA Grants Breakthrough Device Designation to Assay for ACR-368 in Ovarian Cancer

The FDA granted breakthrough device designation to the ACR-368 OncoSignature assay for the identification of patients with ovarian cancer who may derive benefit from the CHK1/2 inhibitor ACR-368.

Peter blume jensenAcrivon oncosignatureInternational federation of gynecologyAcrivon therapeutics incAcrivon therapeuticsAcrivon predictive precision proteomicsAccessed decemberOvarian cancerThe acr 368 oncosignature assay

Neoadjuvant Chemotherapy Does Not Give Survival Benefit Over Chemoradiation in Cervical Cancer

Neoadjuvant chemotherapy preceding surgery did not result in a significant difference in 5-year overall survival rates compared with concomitant chemoradiotherapy in patients with stage IB2 to IIB cervical carcinoma, according to findings from the phase 3 EORTC-55994 trial.

International federation of gynecologyWorld health organizationEuropean organisation for researchInternational federationNeoadjuvant chemotherapy5 year overall survival ratesConcomitant chemoradiotherapyPatients with stage ib2 to iib cervical carcinomaPhase 3 eortc 55994 trial