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Gel patch may one day deliver MS drugs through the nose into the brain
A simplified diagram of the Nose2Brain patch, loaded with biomaterial-based drug particles
N2B-patch Project
N2B-patch Project
Getting traditionally administered drugs into the brain can be challenging, due to the body s protective blood-brain barrier. There may be new hope, however, in the form of a patch that gets shoved up the patient s nose.
The blood-brain barrier is generally a good thing, as it helps keep pathogens in the bloodstream from entering the brain. Unfortunately, though, it also limits the effectiveness of orally or intravenously administered medications – along with nasal sprays – that are used to treat brain disorders such as multiple sclerosis (MS).