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Scientists develop a rapid gene-editing screen to find effects of cancer mutations

MIT researchers found a way to screen cancer-linked gene mutations much more easily and quickly than existing approaches, using a variant of CRISPR genome-editing known as prime editing.

Tyler jacksFrancisco sanchez riveraDavid liuSamuel gouldDavidh kochKoch institute for integrative cancer researchSchool of science fellowship in cancer researchV foundation for cancer researchBroad instituteNational cancer institute center support grantKoch institute frontier awardHarvard university department of chemistryHoward hughes medical institute hanna gray fellowshipLudwig centerNational cancer instituteKoch institute

Rapid Gene-Editing Screen Developed to Detect Cancer Effects

Rapid Gene-Editing Screen Developed to Detect Cancer Effects
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United kingdomDavidh kochSamuel gouldFrancisco sanchez riveraTyler jacksDavid liuHarvard university department of chemistryBroad instituteKoch institute for integrative cancer researchKoch instituteIntegrative cancer researchThales papagiannakopoulosHarvard university departmentChemical biologyNature biotechnology

Cancer: How early-stage cells evade the immune system

In a new study, researchers explain how early-stage cancer cells hide from the immune system. They hope their findings will help improve cancer diagnostics and treatment.

United statesOmer yilmazDaniel landauWael harbAnton bilchikMesothelioma centerMassachusetts institute of technologySyneos healthKoch institute for integrative cancer researchGetty imagesDana farber cancer instituteMassachusetts instituteDana farber cancerIntegrative cancer researchHepatobiliary programProvidence saint john

How Early-stage Cancer Cells Hide From Immune System

How Early-stage Cancer Cells Hide From Immune System
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Omer yilmazTyler jacksPeter westcottJudith agudoDana farber harvardDana farber cancer instituteKoch institute for integrative cancer researchHarvard medical schoolStem cell initiativeKoch instituteCold spring harbor laboratoryNational institutes of health cancer instituteResearch scientist norihiro gotoIntegrative cancer researchScientist norihiroSaori goto

How early-stage cancer cells hide from the immune system

How early-stage cancer cells hide from the immune system
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Omer yilmazTyler jacksJudith agudoPeter westcottHarvard medical schoolKoch instituteDana farber cancer instituteKoch institute for integrative cancer researchCold spring harbor laboratoryIntegrative cancer research