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Chromosomes are organized into loops that regulate genetic information processing, and these loops are extruded by SMC protein complexes like condensin and cohesin. The DNA-binding protein CTCF is crucial for loop positioning along the genome, with its orientation determining loop boundaries. Previo
One in nine women in the developed world will be diagnosed with breast cancer at some point in her life. The prevalence of breast cancer is increasing, an effect caused in part by the modern lifestyle and increased lifespans.