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Mild bee venom appears to be more usable for pharmacology

Compound isolated from Moroccan fungus shows promise to fight triple negative breast cancer

Compound isolated from Moroccan fungus shows promise to fight triple negative breast cancer A compound isolated from a fungus growing on the roots of a flowering plant in Morocco shows promise as a powerful opponent of aggressive triple negative breast cancer, scientists say. They have early evidence that the peptide EnnA, isolated from a fungus living symbiotically with a flowering plant known for its penchant of trapping flies, directly inhibits the natural and powerful cell protector HSP90, which cancer hijacks to help avoid attack by the immune system. EnnA lets the immune system do what it should by getting HSP90 out of the way. We are very excited about how this compound is affecting tumors.

NCI grant enables exploration of cancer-fighting compound isolated from Moroccan fungus

Credit: Kim Ratliff, Augusta University photographer AUGUSTA, Ga. (March 4, 2021) - A compound isolated from a fungus growing on the roots of a flowering plant in Morocco shows promise as a powerful opponent of aggressive triple negative breast cancer, scientists say. They have early evidence that the peptide EnnA, isolated from a fungus living symbiotically with a flowering plant known for its penchant of trapping flies, directly inhibits the natural and powerful cell protector HSP90, which cancer hijacks to help avoid attack by the immune system. EnnA lets the immune system do what it should by getting HSP90 out of the way, says Dr. Ahmed Chadli, biochemist in the Department of Medicine and Georgia Cancer Center at the Medical College of Georgia at Augusta University. We are very excited about how this compound is affecting tumors.

Scientists study nanocapsules in the search for an antibiotic-free approach to superbugs

, and the University of Erlangen-Nuremberg found that nanocapsules loaded with curcumin – a natural compound found in turmeric which is known for its potent anti-inflammatory and anti-tumor properties – were effective against According to the researchers, the curcumin nanocapsules worked not by killing off the bacteria, but rather, by covering them with an “anti-adhesion” coating, thereby disabling its ability to stick to stomach cells where they can cause ill health or even death. This property, as noted by the researchers, can be traced aside from its curcumin content to the nanocapsules’ coating, which contains lysozyme, an enzyme that helps prevent bacterial infections, and dextran sulfate, a water-soluble polysaccharide that binds receptors in the bacteria and in the stomach’s mucosal lining. (Related: Superbugs: Drug-Resistant but Not Herb Resistant)

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