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New Senolytic Approach Promises Treatment for Age-Related Illnesses

New Senolytic Approach Promises Treatment for Age-Related Illnesses
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Tomoyoshi sogaTakaaki furihataChieh lun hsiaoGoro katsuumiTohru minaminoMasataka sugimotoYohko yoshidaYusuke jokiIppei shimizuMasayoshi sudaLiang jiaqiManabu abeShinya fujikiDepartment of animal model developmentNational cerebralCardiovascular center research institute

New Protein Found Linked to Aggressive Breast Cancer Metastases

New Protein Found Linked to Aggressive Breast Cancer Metastases
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United statesInstitute for advanced biosciencesCell discoveryAdvanced biosciences

Study sheds light on enzyme s role in advanced prostate cancer progression

Prostate cancer is the most common cancer in men other than skin cancer, and more than 288,000 new cases are diagnosed every year, according to the American Cancer Society.

United statesNicolas reynoirdSabeen ikramUniversity of maryland baltimoreAmerican cancer societyInstitute for advanced biosciencesUniversity of marylandStanford universityMaryland baltimoreAmerican cancerScience advancesclarifiesVerin greenBaltimore countyAdvanced biosciencesScience advancesProstate cancer

Role of enzyme SMYD3 clarified in prostate ca

A new paper <a href="https://www.science.org/doi/10.1126/sciadv.adi5921">published in Science Advances</a> clarifies how an enzyme called SMYD3 may be involved in prostate cancer’s progression to a more dangerous and aggressive stage. The enzyme’s newly confirmed role makes it a prime potential drug target for preventing metastatic disease, especially given that SMYD3 inhibitors already exist. The new work’s conclusions about SMYD3’s mechanism differ from some previous studies of SMYD3 and reveal new details, opening new research directions.

United statesNicolas reynoirdSabeen ikramUniversity of marylandMethod of researchStanford universityInstitute for advanced biosciencesAmerican cancer societyAmerican cancerVerin greenBaltimore countyAdvanced biosciencesScience advances

Researchers give insight into role of enzyme SMYD3 in prostate cancer progression

Researchers give insight into role of enzyme SMYD3 in prostate cancer progression
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United statesNicolas reynoirdSabeen ikramUniversity of marylandStanford universityInstitute for advanced biosciencesAmerican cancer societyScience advancesVerin greenBaltimore countyAdvanced biosciences