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Mayo study finds colon cancer driven by hereditary gene mutations in 1 in 6 patients

Mayo study finds colon cancer driven by hereditary gene mutations in 1 in 6 patients
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Mayo study finds colon cancer driven by hereditary gene mutations in 1 in 6 patients

Mayo study finds colon cancer driven by hereditary gene mutations in 1 in 6 patients
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Mayo study finds colon cancer driven by hereditary gene mutations in 1 in 6 patients

Mayo study finds colon cancer driven by hereditary gene mutations in 1 in 6 patients
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1 in 6 patients with colorectal cancer found to have inherited genetic mutations

1 in 6 patients with colorectal cancer found to have inherited genetic mutations
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Mayo study finds colon cancer driven by hereditary gene mutations in 1 in 6 patients

 E-Mail ROCHESTER, Minn. A new Mayo Clinic study bolsters evidence that colorectal cancer is often imprinted in family genes and passed on from one generation to the next. In the study, published in Clinical Gastroenterology and Hepatology, researchers within the Mayo Clinic Center for Individualized Medicine found 1 in 6 patients with colorectal cancer had an inherited cancer-related gene mutation, which likely predisposed them to the disease. In addition, the researchers discovered that 60% of these cases would not have been detected if relying on a standard guideline-based approach. We found that 15.5% of the 361 patients with colorectal cancer had an inherited mutation in a gene associated with the development of their cancer, says Niloy Jewel Samadder, M.D., a Mayo Clinic gastroenterologist and hepatologist, who is the study s senior author. We also found that over 1 in 10 of these patients had modifications in their medical or surgical therapy based on the genetic

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