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Exelixis Announces Initiation of the STELLAR-305 Phase 2/3 Pivotal Trial Evaluating Zanzalintinib in Combination with Pembrolizumab in Patients with Previously Untreated Recurrent or Metastatic Head and Neck Cancer

– STELLAR-305 is Exelixis’ first pivotal study in squamous cell carcinoma of the head and neck – – Trial will evaluate the potential of inhibition of VEGF, MET and AXL, which are elevated.

Amy petersonProduct development medical affairsRadiology committeeExelixis incExchange commissionExecutive vice presidentProduct developmentMedical affairsChief medical officerResponse evaluation criteriaSolid tumorsBlinded independent radiology committeeHypertensive crisisPlantar erythrodysesthesiaImpaired wound healingPosterior leukoencephalopathy syndrome

Exelixis Announces Encouraging Results from Expansion Cohort of Phase 1b STELLAR-001 Trial Evaluating Zanzalintinib in Patients with Advanced Kidney Cancer at IKCS 2023

– Results for Exelixis’ next-generation tyrosine kinase inhibitor demonstrated an objective response rate of 38% and a disease control rate of 88% – – Anti-tumor activity was observed in.

United statesSumanta palAmy petersonCity of hope comprehensive cancer centerInternational metastaticInternational kidney cancer symposiumProduct development medical affairsEuropean unionAmerican cancer societyDatabase consortiumExchange commissionExelixis incOral abstractsKidney cancer symposiumClinical professorHope comprehensive cancer center

Exelixis (EXEL) Reports Positive Results from Phase 3 CABINET Pivotal Trial of Cabozantinib

Exelixis (EXEL) Reports Positive Results from Phase 3 CABINET Pivotal Trial of Cabozantinib
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Claire mcconnaugheyJennifer chanSusan hubbardNational clinical trials networkExchange commissionProgram in carcinoidPublic affairsNeuroendocrine tumors at dana farber cancer instituteDrug administrationGastrointestinal cancer centerExelixis incNational institutes of healthEuropean unionCancer therapy evaluation programAlliance for clinical trials in oncologyNational cancer institute

Exelixis Announces Positive Results from Phase 3 CABINET Pivotal Trial Evaluating Cabozantinib in Advanced Pancreatic and Extra-Pancreatic Neuroendocrine Tumors

– CABINET trial will be unblinded and stopped early due to a dramatic improvement in efficacy per a unanimous recommendation by The Alliance for Clinical Trials in Oncology independent Data and.

Jennifer chanProgram in carcinoidExchange commissionNational clinical trials networkNational cancer instituteCancer therapy evaluation programAlliance for clinical trials in oncologyEuropean unionNational institutes of healthExelixis incGastrointestinal cancer centerDrug administrationNeuroendocrine tumors at dana farber cancer instituteClinical trialsSafety monitoring boardWill berg

Exelixis, Inc : Exelixis and Ipsen Announce Positive Results from Phase 3 CONTACT-02 Pivotal Trial Evaluating Cabozantinib in Combination with Atezolizumab in Metastatic Castration-Resistant Prostate Cancer

Exelixis, Inc : Exelixis and Ipsen Announce Positive Results from Phase 3 CONTACT-02 Pivotal Trial Evaluating Cabozantinib in Combination with Atezolizumab in Metastatic Castration-Resistant Prostate Cancer
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United statesUnited kingdomFrance generalNeeraj agarwalVickil goodmanSusan hubbardClaire mcconnaugheyHoward mayerIpsen euronextPublic affairsExchange commissionEuropean unionCancer research at huntsman instituteDrug administrationExelixis incWorld cancer research fund international