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SARS-CoV-2 viral mutations shown to have a limited effect on T cell immunity

New research suggests that viral mutations have a minimal effect on T cell immunity, which could explain the protection provided by vaccination against severe COVID-19, despite the significant loss of neutralizing antibodies.

South africaSouth africanImilian shutterstockScience translational medicineImage creditCoronavirus disease covid 19Ars cov 2Covid 19Evere acute respiratoryEvere acute respiratory syndromeSpike protein

Does vaccine or infection induced immunity better protect against SARS-CoV-2 variants?

A study investigated whether vaccine- or infection-induced immunity is relatively less effective against infection by specific VOCs.

Imilian shutterstockWorld health organizationEuropean centre for disease preventionEuropean centreDisease preventionImage creditCoronavirus disease covid 19Ars cov 2Evere acute respiratoryEvere acute respiratory syndrome

Pfizer COVID-19 vaccine elicits durable specific memory T-cell response

A new preprint describes the protective efficacy of memory T-cells developed in response to the viral antigen, which could offer long-term immunity.

Imilian shutterstockInduces durableStem cell memoryImage creditT cell dependentbGeneralized linear modelsAkaike information criterionTfht cellCoronavirus disease covid 19Ars cov 2T cellImmune responseN vitroIbonucleic acidEvere acute respiratoryEvere acute respiratory syndrome

SARS-CoV-2 clade linked to disease severity in the early phase of the pandemic

SARS-CoV-2 clade linked to disease severity in the early phase of the pandemic
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Imilian shutterstockLiji thomasGlobal initiative on sharing all influenza dataAssociation with disease severityGenomic epidemiologyInitial pandemic waveAssociation with diseaseImage creditGlobal initiativeSharing all influenza dataபடம் கடன்உலகளாவிய முயற்சி