Objective To evaluate the efficacy of covid-19 convalescent plasma to treat patients admitted to hospital for moderate covid-19 disease with or without underlying immunodeficiency (CORIPLASM trial).
Design Open label, randomised clinical trial.
Setting CORIMUNO-19 cohort (publicly supported platform of open label, randomised controlled trials of immune modulatory drugs in patients admitted to hospital with moderate or severe covid-19 disease) based on 19 university and general hospitals across France, from 16 April 2020 to 21 April 2021.
Participants 120 adults (n=60 in the covid-19 convalescent plasma group, n=60 in the usual care group) admitted to hospital with a positive SARS-CoV2 test result, duration of symptoms <9 days, and World Health Organization score of 4 or 5. 49 patients (n=22, n=27) had underlying immunosuppression.
Interventions Open label randomisation to usual care or four units (200-220 mL/unit, 2 units/day over two consecutive days) of covid-19 convalescent
Officials say Russian-speaking person abroad may have paid for the stars to be painted, while social-media accounts linked to Russia promoted images of them
Pastel Shadow is Stéphane Dafflon s first solo exhibition with Air de Paris since 2013 artdaily.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from artdaily.com Daily Mail and Mail on Sunday newspapers.
A replica of the Stone of Possession (Pierre de Possession) was officially unveiled yesterday morning at La Poudriѐre Road marking exactly 267 years since the French took possession of the .