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Age is just a number: Immune cell epigenetic clock ticks independently of organism lifespan

Researchers use epigenetic clock, DNA methylation and mouse model to demonstrate that T cell proliferation can stretch past organism lifespan and acuta lymphoblastic leukemia T cells appear hundreds of years old.

Anoop babu vasandanCaitlin zebleyDavid masopustAndrew soerensZhaoming wangApril muellerVaiva vezysStephen baylinCharles mullighanChristopher hinerIlaria iacobucciHarris goldsteinPeter jonesBen youngbloodCure foundationUniversity of minnesota

Mission Bio Launches Sample Multiplexing for Tapestri to Unlock Critical Single-Cell Insights for Oncology and Genome Editing Markets

Mission Bio Launches Sample Multiplexing for Tapestri to Unlock Critical Single-Cell Insights for Oncology and Genome Editing Markets
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Ilaria iacobucciAnjali pradhanAgilent technologiesTapestri pipeline softwareJude children research hospitalConsort partners for mission bioMission bioMayfield fundDepartment of pathology at stChief product officerPrincipal scientistJude childrenResearch hospitalTapestri platformNovo growthCota capital

Forecasting Cancer-Linked Oncoprotein Condensate Formation

Forecasting Cancer-Linked Oncoprotein Condensate Formation
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Baylor college of medicineUnited statesBappaditya chandraMadan babuScott gormanIlaria iacobucciBrittany piosoXin zhouDiana mitreaDaniel jaroszCharles mullighanDavid baggettJohn bollingerSwarnendu tripathiJinghui zhangYongsheng li

To wipe childhood cancer off map, scientists must chart its genomic landscape

To wipe childhood cancer off map, scientists must chart its genomic landscape
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United statesAshley hillMichael ruschPradyuamna baviskarR jinghui zhangJames downingMeenakshi devidasIlaria iacobucciDiane flaschMary rellingJian wangStephen riceXiaotu maSima jehaDanielas gerhardColleen reilly

Analysis reveals origins of a leukemia that straddles diagnostic categories

Analysis reveals origins of a leukemia that straddles diagnostic categories
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Cyrus mehrKirsten dickersonZhaohui guJing maIlaria iacobucciWilliam evansMary rellingRyan hiltenbrandWenjian yangTamara westoverXiaolong chenXiaotu maJeffery klcoKathryn robertsJunj yangCharles mullighan