observation until and all limited by all kinds of confounding factors. what we know for certain is that alcohol is a cardio toxin. it s actually poison to the heart muscle. large amounts of alcohol can cause cardiomyopathy, a weakness of the heart. binge drinking can cause arrhythmias like iatrial fibrillation. from a global health perspective we know that alcohol causes probably somewhere between 2 million and 3 million cases of cancer in the world every year in. head and neck cancer, stomach cancer. there s never within a, quote, safe dose of alcohol. when my patients ask me about how much, you know, they should drink, i remind them that a glass of wine would make them feel better, but may not make them live longer.