COVID variants HV.1 and JN.1 are emerging strains causing concern. HV.1, an Omicron spin-off, dominates in the US but shows no increased threat. JN.1, derived from Pirola, appears in the UK, US, Iceland, Portugal, and Spain, displaying greater immune evasion. Both share common symptoms—fever, cough, fatigue, nasal issues—with JN.1 adding diarrhea and headaches. While no unique symptoms are identified, caution and testing are crucial in understanding and managing these evolving strains.