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The subcommittee will come to order. Thank you all very, very much and, again, we apologize for being late. Days take on a life of their own. But i wanted to say good morning, dr. Collins. Welcome back to labor hhs, the appropriations subcommittee. Let me just say thank you on behalf of the of the subcommittee for hosting members of the subcommittee for the site visit at the nih campus last week. We had a wonderful opportunity to learn more about nihs work. We met with the researchers who were working to cure Sickle Cell Disease, to develop treatments for major depression, shrink and treat cancer tumors in children. We heard from participants whose lives have been changed by Clinical Trials. So it was a moving an informative but a very moving experience as well. Let me welcome our witnesses, including the five institute and Center Directors who join us today and in addition, and always a great addition, dr. Francis collins whos joined us many times, director of the National Institutes

New yorkUnited statesPuerto ricoDistrict of columbiaNew mexicoPatricia flatley brennanFrancis collinsBarack obamaMatt damonPatty brennanHerrera butlerJosh gordonChristopher austinJust saySickle cellInstitute center