In patients with minor nondisabling acute ischemic stroke, treatment with dual antiplatelet therapy was noninferior to treatment with IV alteplase, according to the results of the ARAMIS trial.The researchers randomly assigned 760 patients (median age, 64 years; 31% women) with minor nondisabling acute ischemic stroke — defined as NIH Stroke Scale score of 5 or less, plus 1 point or less on
A process that uses occlusion/release cycles on upper limb arteries is associated with greater neurologic function after acute ischemic stroke than usual care, new research shows.
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High-risk, nonstenotic intracranial plaque appears to be a more important cause of embolic stroke of undetermined source (ESUS) than previously appreciated, according to findings from a Chinese imaging study.
Researchers led by Lin Tao, MD (General Hospital of Northern Theater Command, Shen Yang, China), showed that this type of plaque was more common and more vulnerable on the ipsilateral versus contralateral side, differences that were not seen in patients with acute ischemic strokes related to small-vessel disease (SVD).
“The present study provides the first evidence supporting an etiologic role for high-risk nonstenotic intracranial plaque in patients with ESUS,” they write, noting that “the optimal preventive strategies in these patients remain unclear.”