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Hijacked immune activator promotes growth and spread of colorectal cancer
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High-throughput metabolic profiling of single cells
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Blood stem cells make brain tumors more aggressive
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Brain tumor cells with a certain common mutation reprogram invading immune cells. This leads to the paralysis of the body s immune defense against the tumor in the brain. Researchers from Heidelberg, Mannheim, and Freiburg discovered this mechanism and at the same time identified a way of reactivating the paralyzed immune system to fight the tumor. These results confirm that therapeutic vaccines or immunotherapies are more effective against brain tumors if active substances are simultaneously used to promote the suppressed immune system.
Vaccination against mutated protein tested in brain tumor patients for the first time
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