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Research News Research News 2021-06-29 Researchers have identified a new treatment candidate that appears to not only halt neurodegenerative symptoms in mouse models of dementia and Alzheimer s disease, but also reverse the effects of the disorders. The team, based at Tohoku University, published their results on June 8 in the International Journal of Molecular Sciences. The treatment candidate has been declared safe by Japan s governing board, and the researchers plan to begin clinical trials in humans in the next year. There are currently no disease-modifying therapeutics for neurodegenerative disorders such as Alzheimer s disease, Lewy body dementia, Huntington disease and frontotemporal dementia in the world, said paper author Kohji Fukunaga, professor emeritus in Tohoku University s Graduate School of Pharmaceutical Sciences. We discovered the novel, disease-modifying therapeutic candidate SAK3, which, in our studies, rescued neurons in most protein-misfolding, neurodege

Japan generalKohji fukunagaJing xuIchiro kawahataHisanao izumiTohoku university graduate school of pharmaceutical sciencesInternational journal of molecular sciencesDrug administrationTohoku universityInternational journalGraduate schoolஜிங் ஐயூசர்வதேச இதழ் ஆஃப் மூலக்கூறு அறிவியல்தோஹோக்கு பல்கலைக்கழகம்சர்வதேச இதழ்பட்டதாரி பள்ளி