ADT May Cause Side Effects in Prostate Cancer Patients by Angela Mohan on January 6, 2021 at 12:16 PM
ADT reduces the level of testosterone and other androgens in the body causing fatigue, depression and cognitive impairment among prostate cancer patients.
Moffitt Cancer Center researchers are investigating whether inflammation in the body, a side effect of ADT, contributes to these symptoms in prostate cancer patients.
In a new study published in the journal
Cancer, they pinpoint a specific inflammation marker that is associated with increased fatigue in this group of patients. This is the first study that we know of that examines the association between inflammation and symptoms of fatigue, depression or cognitive impairment in prostate cancer patients receiving ADT, said Heather Jim, Ph.D., corresponding author and co-leader of the Health Outcomes & Behavior Program at Moffitt.