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Neoadjuvant Dendritic Cell Vaccine–Based Regimen Elicits pCRs in Early-Stage HER2+ Breast Cancer

Neoadjuvant Dendritic Cell Vaccine–Based Regimen Elicits pCRs in Early-Stage HER2+ Breast Cancer
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United statesHeather hanBreast oncologyMoffitt cancer center

Dr Han on the Investigation of Neoadjuvant Therapy Plus a Dendritic Cell Vaccine in HER2+ Breast Cancer

Heather Han, MD, discusses initial safety and efficacy results from the phase 2 NATASHA trial in patients with early-stage HER2-positive breast cancer.

Heather hanDepartment of breast oncologyMoffitt cancer centerBreast oncologyPhase 1 2 natasha trial nct05325632Early stage her2 positive breast cancer

Pepinemab/Trastuzumab With Dendritic Cell Vaccine and Adoptive T-Cell Therapy Under Evaluation in HER2+ Breast Cancer

A treatment regimen consisting of pepinemab plus trastuzumab and a dendritic cell vaccine, followed by autologous CD4-positive T cells, is under investigation in a phase 1 trial in patients with metastatic HER2-positive breast cancer.

United statesHeather hanBreast oncologyMoffitt cancer centerHer2 positive breast cancerBreast cancerCd4 positivet cellsAsco annual meetingDendritic cell vaccine

OAKLEAF – Behind a strong pitching performance from phenom sophomore Charlotte “Charley” Maddox and a two-run homer by Amya Mirelez, Oakleaf High (10-11) shut out Nease, 7-0, sending the …

Mariyah sanchezCharlotte charley maddoxAmaya marillaAddison gishCharley maddoxKissimmiee klassicAmya mirelezHeather hanLee wardlawCiara gibsonMeshayla pettawayChristina thompsonJaidyn collinsOakleaf highLake brantleyFinal four

Gedatolisib, Fulvestrant, and Palbociclib Triplet Under Investigation in HR+/HER2– Breast Cancer

The combination of gedatolisib and fulvestrant with or without palbociclib is under evaluation in the phase 3 VIKTORIA-1 trial for the treatment of patients with PIK3CA-mutated or wild-type hormone receptor–positive/HER2-negative breast cancer who have previously progressed on first-line therapy.

San antonioUnited statesHeather hanBreast oncologyMoffitt cancer centerAntonio breast cancer symposiumHase 3 viktoria 1 trial nct05501886Pik3ca mutatedHormone receptor hr positive her2 negative breast cancerFirst line therapy witha cdk4 6 inhibitor2023 aacr annual meeting