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Study links deprivation with risk of dying from sepsis

Study links deprivation with risk of dying from sepsis
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United kingdomVan staaTjeerd van staaXiaomin zhongRon danielsColin brownCare research manchester biomedical centreHealth data research united kingdomUnited kingdom sepsisNational institute for healthUnited kingdom health security agencyUniversity of manchesterNational instituteProfessor tjeerdUnited kingdom sepsis trustAntimicrobial resistance

How can Norway get more out of health data?

How can Norway get more out of health data?
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United kingdomAndrew morrisChristine wergelandOslo university hospitalHealth data research united kingdomUniversity of osloNorwegian university of life sciencesAssociation of the pharmaceutical industryOslo science cityLife sciencesPharmaceutical industryOslo cancer clusterLife science clusterNorway life scienceOslo science city arenaManaging director

Medicine in the 4th Industrial Revolution | University of Oxford

Medicine in the 4th Industrial Revolution | University of Oxford
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United kingdomAndrew morrisHealth data research united kingdomProfessor andrew morris

Ethnic differences in early onset multimorbidity and associations with health service use, long-term prescribing, years of life lost, and mortality: A cross-sectional study using clustering in the UK Clinical Practice Research Datalink

Fabiola Eto and co-workers study variations in comorbidity, service use and health outcomes by ethnicity and socioeconomic position, among people aged 16-39 years.

United statesUnited kingdomUnited arab emiratesQueen mary apocritaSanjay basuNovo nordiskUnited kingdom clinical practice research datalinkAcademy of medical sciencesInternational society for affective disordersUnited kingdom medical research councilMerck sharp dohmeOffice for national statisticsEuropean college of neuropsychopharmacologyAstra zenecaLife sciences consortiumTakeda development centre americas inc

Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance

The CONSORT (CONsolidated Standards Of Reporting Trials) 2010 statement is the standard guideline for reporting completed randomised trials. The CONSORT Dose-finding Extension (DEFINE) extends the guidance (with 21 new items and 19 modified items) to early phase dose-finding trials with interim dose escalation or de-escalation strategies. Such trials generally focus on safety, tolerability, activity, and recommending dosing and scheduling regimens for further clinical development. These trials are often inadequately reported, hampering their informativeness and making evidence informed decisions difficult. The CONSORT-DEFINE guidance aims to develop an international, consensus driven guideline for reporting early phase dose-finding trials to promote transparency, completeness, reproducibility, and facilitate the interpretation of the results. The CONSORT-DEFINE guidance provides recommendations for essential items that should be reported in early phase dose-finding trials to promote gr

Glasgow cityUnited kingdomWest midlandsUnited kingdom generalUnited statesDaiichi sankyoJanssen clovisOxford biotherapeuticsLilly incyteCelgene eisaiSumitomo dainippon pharmaGenentech rocheBristol myers squibbAstra zenecaMerck seronoSanofi aventis