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Plasmodium vivax malaria is a mosquito-borne illness that causes significant morbidity. However, the household and healthcare provider costs of the disease are unknown. A new study published in the open-access journal
PLOS Medicine by Dr Angela Devine at Menzies School of Health Research in Australia, and colleagues estimate the global economic burden of P. vivax for the first time using country-level data.
Researchers first estimated household and healthcare provider P. vivax costs, then collated and combined these data with national case estimates for 44 endemic countries in 2017. The resulting global cost estimate was US$359 million.
The authors wanted to explore how these cost estimates might change with widespread access to radical cure. Radical cure refers to a sustained clinical response and prevention of future relapses caused by the dormant liver parasites of P. vivax, requiring complete elimination of both the blood and liver stages of the parasites. New tre
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Artificial intelligence promises to be a powerful tool for improving the speed and accuracy of medical decision-making to improve patient outcomes. From diagnosing disease, to personalizing treatment, to predicting complications from surgery, AI could become as integral to patient care in the future as imaging and laboratory tests are today.
But as University of Washington researchers discovered, AI models like humans have a tendency to look for shortcuts. In the case of AI-assisted disease detection, these shortcuts could lead to diagnostic errors if deployed in clinical settings.
In a new paper published May 31 in
Nature Machine Intelligence, UW researchers examined multiple models recently put forward as potential tools for accurately detecting COVID-19 from chest radiography, otherwise known as chest X-rays. The team found that, rather than learning genuine medical pathology, these models rely instead on shortcut learning to draw spurious associations between me
A randomized controlled trial found that tai chi is about as effective as conventional exercise for reducing waist circumference in middle-aged and older adults with central obesity. Central obesity, or weight carried around the midsection, is a major manifestation of metabolic syndrome and a common health problem in this cohort. The findings are published in Annals of Internal Medicine.
Credit: The Lundquist Institute
LOS ANGELES (May 31, 2021) Today The Lundquist Institute announced that its investigators contributed data from several studies, including data on Hispanics, African-Americans and East Asians, to the international MAGIC collaboration, composed of more than 400 global academics, who conducted a genome-wide association meta-analysis led by the University of Exeter. Now published in
Nature Genetics, their findings demonstrate that expanding research into different ancestries yields more and better results, as well as ultimately benefitting global patient care. Up to now nearly 87 percent of genomic research of this type has been conducted in Europeans. We are very excited about contributing to this global study, said Dr. Jerome I. Rotter, Investigator and Director of the Institute for Translational Genomics and Population Sciences at The Lundquist Institute and Professor of Pediatrics and Human Genetics at the Geffen School of Medicine at UCLA.