How mutation in microglia elevates Alzheimer's risk miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
New MIT research shows that human microglia with the R47H/+ mutation in the TREM2 protein exhibit several deficits related to Alzheimer’s pathology. Mutant microglia are prone to inflammation, yet are worse at responding to neuron injury and less able to clear harmful debris, including amyloid beta.
How a mutation in microglia elevates Alzheimer's risk sciencedaily.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencedaily.com Daily Mail and Mail on Sunday newspapers.
A new candidate drug reduced inflammation and improved memory in human cell cultures and Alzheimer’s mouse models. The work was co-led by the lab of Li-Huei Tsai at the Picower Institute for Learning and Memory.