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Researchers Uncover New Ways to Determine Effectiveness of Cancer Therapies

There have been many advances in therapies against pathways altered in cancer cells. However, there are targeted therapies that remain less effective. Now, researchers from Indiana University School of Medicine report they have discovered a new way to determine how effective a drug might be against cancer. 

Researchers find strategy to reduce treatment-related complication for blood cancer patients

Researchers find strategy to reduce treatment-related complication for blood cancer patients ANI | Updated: Jan 10, 2021 22:33 IST Washington [US], January 10 (ANI): A study published in the New England Journal of Medicine by researchers of the Indiana University Melvin and Bren Simon Comprehensive Cancer Center sheds light on preventing a treatment-related complication of blood stem cell transplantation for blood cancer patients. Sherif Farag, MD, PhD, found that using a drug approved for Type 2 diabetes reduces the risk of acute graft-versus-host disease (GVHD), one of the most serious complications to lifesaving blood stem cell transplantation in leukaemia. GVHD occurs in more than 30 per cent of patients and can lead to severe side effects and potentially fatal results. Farag is the Lawrence H. Einhorn Professor of Oncology and professor of medicine at IU School of Medicine, a member of the IU Simon Comprehensive Cancer Center and progra

IU research findings could reduce treatment-related complication for blood cancer patients

Credit: IU School of Medicine INDIANAPOLIS Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center published promising findings today in the New England Journal of Medicine on preventing a common complication to lifesaving blood stem cell transplantation in leukemia. Sherif Farag, MD, PhD, found that using a drug approved for Type 2 diabetes reduces the risk of acute graft-versus-host disease (GVHD), one of the most serious complications of blood stem cell transplantation. GVHD occurs in more than 30 percent of patients and can lead to severe side effects and potentially fatal results. Farag is the Lawrence H. Einhorn Professor of Oncology and professor of medicine at IU School of Medicine, a member of the IU Simon Comprehensive Cancer Center and program and medical director of the hematological malignancies and bone marrow and blood stem cell transplantation at IU Health.

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