Severe heart attacks often progress to end-stage heart failure because the dearth of heart muscle cells diminishes pumping power of the heart’s left ventricle. The damaged heart, unable to repair itself, deteriorates and enlarges into congestive hear
The modified mRNA delivered after experimental heart attacks transiently allows heart muscle cells to proliferate, leading to reduced infarct size and improved heart performance compared to untreated animals. Jianyi.
Modified mRNA Boosts Heart Attack Recovery in Animal Models miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
Single-nucleus RNA-sequencing in a newborn pig model showed increased cell cycle activity and proliferation in cardiomyocytes, which helped remuscularize the left ventricle after experimental heart attack.
Changed gene expression after heart surgery extends cardiomyocyte regeneration miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.