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Research: Varied COVID-19 Risk Among Immunocompromised Patients

Research: Varied COVID-19 Risk Among Immunocompromised Patients
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Virologic Rebound Occurs in ~20 Percent Receiving Nirmatrelvir-Ritonavir

Virologic rebound more common among those who started therapy within 2 days of symptom onset

United statesGregorye edelsteinHealthday news

One in five patients experience rebound COVID after taking Paxlovid, new study finds

One in five patients experience rebound COVID after taking Paxlovid, new study finds
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One in five patients experience rebound COVID

<p>A new study by investigators from <a href="https://www.massgeneralbrigham.org/">Mass General Brigham</a> found that one in five individuals taking Nirmatrelvir-ritonavir therapy, commonly known as Paxlovid, to treat severe symptoms of COVID-19, experienced a positive test result and shedding of live and potentially contagious virus following an initial recovery and negative test—a phenomenon known as virologic rebound. By contrast, people not taking Paxlovid only experienced rebound about 2 percent of the time. Results are published in <a href="https://www.acpjournals.org/journal/aim/authors1"><em>Annals of Internal Medicine</em></a>.</p>

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One in five patients experience rebound COVID after taking Paxlovid

One in five patients experience rebound COVID after taking Paxlovid
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Harvard universityUnited statesGregorye edelsteinDessie tienJacobe lemieuxJonathon liRockib uddinMark siednerManishc choudharySarahp hammondShruti sagarMamadou barryZahra reynoldsAmyk barczakYumeko kawanoRebeccaf gilbert