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Conditioning Regimens for Stem Cell Transplantation

Clinical Scenario: A 38-Year-Old Man with Ph+ ALL

Bonnie Dirr, APRN, introduces a clinical scenario of a patient who received an allogeneic stem cell transplant from a sibling donor to begin the panel’s discussion of graft versus host disease.

GVHD Incidence and Pathophysiology

Mahasweta Gooptu, MD, reviews statistics on graft versus host disease and explains the desired graft versus leukemia effect.

Stem Cell-Derived CAR T Cells Open Door To Universal Donor Cell Lines

Induced pluripotent stem cells (iPSC), a continuing muse in cell therapy research, could potentially be used to improve flaws associated with conventional CAR T therapy.

The Importance of Early Treatment of Chronic GVHD

Drs Paczesny and Chen explain the importance of treating chronic GVHD as early as possible, and whether steroids are still the standard first-line treatment.

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