<p><strong>To speed up their growth, leukemia cells typically activate the recycling of cellular structures – enabling them to dispose of defective components and better supply themselves with building materials. Researchers at Goethe University Frankfurt have now shown that leukemia cells with a very common mutation activate specific genes that are important for this recycling process. Their findings, published in the journal Cell Reports, open up new therapeutic options for the future.</strong></p>
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Twist Bioscience Corporation: Twist Bioscience and Vivlion Partner to Generate gRNA Libraries for CRISPR Applications
Twist Bioscience Corporation (Nasdaq: TWST), a company enabling customers to succeed through its offering of high-quality synthetic DNA using its silicon platform, and Vivlion GmbH, a company providing next-generation CRISPR gRNA libraries and screening services for the global R&D market, today announced a collaboration for the generation of gRNA libraries for CRISPR applications. CRISPR\Cas is a powerful functional genomics tool used for a wide range of applications including genome engineering and target discovery for drug development. Research using CRISPR continues to accelerate into many different areas. This collaboration combines Twist s ability to generate highly uniform long oligos at scale with Vivlion s ability to translate these into equally highly uniform CRISPR libraries for the next generation of high-throughput CRISPR screenings, said Emily M. Lep