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Korea Advanced Institute of Science and Technology The interface is easy to insert into the body when dry, but behaves ‘stealthily’ inside the brain when wet Figure 1. Schematic of Hydrogel Hybrid Brain-Machine Interfaces Professor Seongjun Park’s research team and collaborators revealed a newly developed hydrogel-based flexible brain-machine interface. To study the structure of the brain or to identify and treat neurological diseases, it is crucial to develop an interface that can stimulate the brain and detect its signals in real time. However, existing neural interfaces are mechanically and chemically different from real brain tissue. This causes foreign body response and forms an insulating layer (glial scar) around the interface, which shortens its lifespan.

South koreaXuanhe zhaoPolina anikeevaHyunwoo yookMachine interfaces korea advanced institute of scienceNational research foundationKorea medical device development fundNature communications onGlobal initiative programHydrogel hybrid brain machine interfacesKorea advanced instituteSeongjun parkNature communicationsProfessor polina anikeevaProfessor xuanhe zhaoInitiative program