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New insights into migraine etiology: the role of hepatocyte growth factor

COVID-19 increases Alzheimer s risk

The study explores the interconnected risks between COVID-19 and Alzheimer's Disease (AD), highlighting how SARS-CoV-2 can aggravate AD pathology through neuroinflammation and neurodegeneration. It raises significant concerns about the long-term cognitive implications of COVID-19, especially among those already at risk for AD.

Molecular insights into drug-induced GDF15 regulation in cancer cells and cardiomyocytes

A recent study elucidated the molecular mechanisms of drug-induced regulation of growth differentiation factor 15 (GDF15).

Quantifying chemotherapeutic cytotoxicity in glial cells using AI-driven label-free cell analysis

In this application note, Sartorius emphasizes the importance of understanding the complex response of tumor cells, particularly glioblastomas, to cytotoxic chemotherapeutic compounds in neuro-oncology research. The Incucyte ®  AI Cell Health Analysis Software Module accurately segments and classifies individual cells as live or dead using pre-trained neural networks. This approach enables ef

AI-driven label-free image analysis for assessing chemotherapeutic cytotoxicity in glial cells

In this application note, Sartorius demonstrates a robust in vitro assay using the Incucyte ® Live-Cell Analysis System and AI-driven analytics to assess the cytotoxic effects of chemotherapeutics in glioblastoma multiform (GBM) cells. The study shows concentration-dependent effects across different glial cell types and highlights the system s potential for screening therapeutic candidates. The Incucyte system offers automated analysis, accurate cell segmentation, and live/dea

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