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ADA 2021 Roundup: SoliMix Trial; Byetta for Teens; Driving in Hypoglycemia

email article Below are a few more research highlights. SoliMix Trial When managing type 2 diabetes, the once-daily iGlarLixi (Soliqua) edged out the twice-daily premix insulin analog BIAsp 30, according to the SoliMix trial. The 26-week, open-label trial included adults with poorly controlled type 2 diabetes, defined as a baseline HbA1c between 7.5% and 10%. All participants were on basal insulin, as well as oral antidiabetic agents. Approved in 2016, iGlarLixi is a fixed-ratio combination of insulin glargine 100 U/mL (iGlar) and the GLP-1 receptor agonist lixisenatide (Lixi). BIAsp 30 is biphasic insulin aspart 30/70, and is a premixed injectable insulin analogue with 30% soluble, rapid-acting insulin aspart plus 70% intermediate-acting protamine-bound aspart.

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