The Robert Koch Institute for infectious diseases reported 203,136 positive tests in the last 24 hours, 69,600 cases more than the same day a week ago.
German lawmakers are due to debate introducing a bill making vaccination against COVID-19 mandatory. The idea is facing resistance from politicians as well as ordinary Germans.
Germany has registered more than 100,000 new Covid-19 infections in the past 24 hours, according to data released by the country's public health agency on Wednesday.
Amid an ongoing resurgence across the world due to rapid spread of Omicron variant, the global coronavirus caseload has topped 297 million in the last 24 hours