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Unlocking the Secrets of the Cell: Scientists Dive Into the Dark Hole of the Nuclear Pore Complex

Unlocking the Secrets of the Cell: Scientists Dive Into the Dark Hole of the Nuclear Pore Complex
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Edward lemkeChao ruanEdwarda lemkeMaziar heidariChristopherd reinkemeierAgnieszka obarska kosinskaMarc siggelMartin beckGerhard hummerSofya mikhalevaMiao yuSara minguInstitute of molecular biology mainzIllustration nuclear poreMax planck institute of biophysicsDepartment of theoretical biophysics

Inherited Neurodegenerative Diseases Linked to Cell Self-Digestion

Inherited Neurodegenerative Diseases Linked to Cell Self-Digestion
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Wiggly proteins guard the genome: Dynamic network in the pores of the nuclear envelope blocks dangerous invaders

Wiggly proteins guard the genome: Dynamic network in the pores of the nuclear envelope blocks dangerous invaders
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Edward lemkeGerhard hummerMax planck institute of biophysicsInstitute of molecular biology mainzMax planck instituteSynthetic biophysicsJohannes gutenberg university mainzAdjunct directorMolecular biology mainz

Study finds how intrinsically disordered proteins guard genome

The protection and preservation of the genetic material by tiny holes in the cell nucleus is crucial for healthy ageing. German researchers from the Synthetic Biophysics of Protein Disorder Group at Johannes Gutenberg University Mainz and the Department of Theoretical Biophysics at the Max Planck Institute of Biophysics in Frankfurt am Main have literally filled a gap in our knowledge of the composition and operation of these nuclear pores.

Gerhard hummerEdward lemkeMartin beckMax planck institute of biophysicsInstitute of molecular biology mainzDepartment of theoretical biophysicsSynthetic biophysicsProtein disorder groupJohannes gutenberg university mainzTheoretical biophysicsMax planck instituteAdjunct directorMolecular biology mainzUard genomeHealthy agingUclear pores

Study finds how intrinsically disordered proteins guard genome

Study finds how intrinsically disordered proteins guard genome
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Edward lemkeMartin beckGerhard hummerInstitute of molecular biology mainzMax planck institute of biophysicsDepartment of theoretical biophysicsSynthetic biophysicsProtein disorder groupJohannes gutenberg university mainzTheoretical biophysicsMax planck instituteAdjunct directorMolecular biology mainz