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Jnana Therapeutics Presents Additional Data from Phase 1a Clinical Study of JNT-517 at SSIEM Annual Symposium

JNT-517 demonstrated sustained, dose-dependent pharmacodynamic effects and was safe and well tolerated in healthy volunteers Phase 1b study is ongoing in individuals with PKU BOSTON, Aug. 31, 2023 (GLOBE NEWSWIRE)

United statesGeorge vratsanosCaryo hardingDrug administrationScience university school of medicineGenetics at oregon healthInborn errorsAnnual symposiumMedical geneticsOregon healthScience university schoolChief medical officerClinical trialPediatric disease designation

Jnana Therapeutics Announces Dosing of First Participant in Phase 1b Clinical Trial of JNT-517 in Individuals with PKU

Jnana Therapeutics Announces Dosing of First Participant in Phase 1b Clinical Trial of JNT-517 in Individuals with PKU
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Israel generalUnited statesJohn throupCaryo hardingGeorge vratsanosJosh rappaportBain capital life sciencesHead of development at jnana therapeuticsJnana therapeutics incDrug administrationPotential first in class oral treatmentStudy follows positive clinical proofMechanism dataOral presentationStudy resultsInborn errors

Jnana Therapeutics Announces Dosing of First Participant in Phase 1b Clinical Trial of JNT-517

JNT-517 is a Potential First-in-Class Oral Treatment for PKU; Phase 1b Study Follows Positive Clinical Proof of Mechanism Data in Healthy Individuals

United statesIsrael generalJosh rappaportCaryo hardingJohn throupGeorge vratsanosBain capital life sciencesDrug administrationHead of development at jnana therapeuticsPotential first in class oral treatmentStudy follows positive clinical proofMechanism dataOral presentationStudy resultsInborn errorsAnnual symposium

Forming Meaningful PharmaAcademia Partnerships

In large pharma, investment in R&D is increasingly expensive. In academia, there is pressure to produce high-profile science for the improvement.

United statesNorthern ostrobothniaCity ofUnited kingdomSouthwest finlandDanuta jeziorskaJim hughesPeter schultzGeorge vratsanosJames daviesUniversity college londonDoor collaborative enterprisesJanssen pharmaceutical companies of johnsonResearch institutionsGenomics institute of the novartis research foundationClinical development

Collaborating With Academia For Drug Discovery Targeting Immune-Mediated Diseases

Last year, Janssen Biotech and the University of Oxford established a collaboration to understand pathogenic pathways driving immune-mediated.

United kingdomCity ofGeorge vratsanosLuke deveyYale universityArthritis therapy acceleration programmeUniversity of oxfordUniversity of birminghamNational health serviceColumbia universityKennedy trust for rheumatology researchCell technology uncovering pathogenic pathwaysImmunology therapeutic area at janssen research developmentYork universityRoyal college of surgeons edinburghJanssen biotech