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Scientists identify and show how to target a key tumor defense against immune attack

Scientists identify and show how to target a key tumor defense against immune attack
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Ludwig lausanneLudwig lausanne matteo morottiDenarda dangaj lanitiDangaj lanitiGeorge coukosAlizee grimmTechnical university of munichMatteo morottiDirector george coukosTechnical university

Ludwig Lausanne scientists identify and show how to target a key tumor defense against immune attack

A Ludwig Cancer Research study has discovered how a lipid molecule found at high levels within tumors undermines the anti-cancer immune response and compromises

George coukosDenarda dangaj lanitiAlizee grimmLudwig lausanne matteo morottiDangaj lanitiLudwig lausanneSwiss cancer league foundationSwiss cancer centerCancera foundationTechnical university of munichBiltema foundationLausanne university hospitalPaul matson foundationBiomarker discovery lab at ludwig lausanneA ludwig cancer researchDepartment of oncology

Ludwig Lausanne Reveals How to Target Tumor s Immune Defense

Ludwig Lausanne Reveals How to Target Tumor s Immune Defense
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Denarda dangaj lanitiGeorge coukosLudwig lausanne matteo morottiAlizee grimmDangaj lanitiLudwig lausanneSwiss cancer centerTechnical university of munichBiomarker discovery lab at ludwig lausanneLudwig cancer researchDepartment of oncologyCancera foundationA ludwig cancer researchGerman research foundationLausanne university hospitalSwiss cancer league foundation

Immune cell networks key to success of personalized cancer treatment

Through an analysis of tumor samples collected over time from patients with advanced melanoma, a Ludwig Cancer Research study has identified a set of preexisting conditions in tumors that predict whether such patients are likely to respond to a personalized immunotherapy known as adoptive T cell therapy (ACT) using tumor-infiltrating lymphocytes (TIL).

Ludwig lausanne david barrasDenarda dangaj lanitiEleonora ghisoniGeorge coukosJohanna chiffelleLudwig institute for cancer researchLudwig cancer researchLudwig lausanneDavid barrasBranch director george coukosScience immunologyLausanne branchLudwig instituteCancer research

Tumor Immune Networks Boost Response to Personalized Immunotherapy

Tumor Immune Networks Boost Response to Personalized Immunotherapy
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Switzerland generalJohanna chiffelleLudwig lausanne david barrasPaul matsonDavid barrasBristol meyers squibbDenarda dangaj lanitiLudwig lausanneEleonora ghisoniGeorge coukosLausanne university hospitalDepartment of oncologyBiomarker discovery lab at ludwig lausanneSwiss national foundationLudwig cancer researchSwiss cancer center