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Ovarian Cancer: New Biological Markers Found That May Predict Which Patients Won t Respond to Chemotherapy

Using a novel proteogenomic strategy and a variety of machine learning tools, investigators from the Icahn School of Medicine at Mount Sinai and colleagues have identified a 64-protein signature that may predict a subset of ovarian cancer patients who are unlikely to respond to chemotherapy.

United statesBaylor college of medicineFrancesca petraliaAmandag paulovichMarcin cieslikNoshad hosseiniYajue huangBing zhangUmut ozbekHenry rodriguezAmanda paulovichSamuelc mokMehdi mesriScotth kaufmannSeungyeul yooJeffreyr whiteaker

Mount Sinai bioengineers send cardiac muscle samples into space to study heart cell biology in microgravity

New York NY (SPX) Nov 16, 2023 - Mount Sinai s Cardiovascular Research Institute is sending bioengineered human heart muscle cells and micro-tissues into space for the first time on NASA s 29th SpaceX commercial resupply services m

New yorkUnited statesDavid sachsMount sinai cardiovascular research instituteIcahn school of medicine at mount sinaiGenomic sciences at icahn mount sinaiMount sinaiCardiovascular research instituteInternational space stationIcahn schoolSpace tangoKevin costaAssociate professorIcahn mountCardiovascular researchAssistant professor

Mount Sinai Bioengineers Send Cardiac Muscle Samples Into Space to Study Heart Cell Biology in Microgravity

Findings will help scientists understand how microgravity impacts the ability of human heart cells to withstand the stresses of space travel

David sachsIcahn school of medicine at mount sinaiGenomic sciences at icahn mount sinaiMount sinai cardiovascular research instituteMount sinaiCardiovascular research instituteInternational space stationIcahn schoolSpace tangoKevin costaAssociate professorIcahn mountCardiovascular researchAssistant professorGenomic sciences

Mount Sinai Researchers Find More Than 4,700 Gene Clusters Crucial for Prognosis in 32 Cancer Types

Mount Sinai Researchers Find More Than 4,700 Gene Clusters Crucial for Prognosis in 32 Cancer Types
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East harlemNew yorkUnited statesNew providencePeng xuKarin eskenaziNational institutes of healthIcahn school of medicine at mount sinaiMerck coGenome researchGenomic sciencesMount sinai centerNovo nordiskMount sinai health systemHealth systemAssociation of american medical colleges

Researchers find more than 4,700 gene clusters crucial for prognosis in 32 cancer types

Researchers find more than 4,700 gene clusters crucial for prognosis in 32 cancer types
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Peng xuGenome researchGenomic sciencesMount sinai centerMount sinai health systemMount sinai healthTransformative disease modelingBin zhangResearch professorTransformative diseaseCancer genome atlas