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Genetic melting pot: Study unveils complex admixture in European ancestry populations

In a recent Nature Communications study, researchers revealed that Europeans and European Americans possess a significant subcontinental genetic admixture, challenging the notion that these populations are homogenous. This finding suggests the need to re-evaluate genetic epidemiology studies that may have overlooked the influence of admixture on disease associations and trait heritability in these groups.

Human genome reboot better reflects global population

Transcripts for BBCNEWS HARDtalk 20240604 03:43:00

are we really sure that is very protective against african population, given our own richness and in our own genome diversity? we all know that for many people, for many drugs and many vaccines out there, we are, because we are genetically very different, we might respond differently and it would have been fair enough and equitable enough to accelerate some clinical trials in africa to see how the african people respond. ok, so we know that african genomes are the most diverse, as you ve just said, and they re the oldest. there are things in the human genome that we can t study anywhere else but in africa and sub saharan africa is where 70% of all pathogens with pandemic potential emerge. and yet, as we said, only a fraction of global scientific research money goes into africa. so could africa, then, given it s got this rich diversity, become a global leader when it comes to scientific research and finding breakthroughs

Transcripts for BBCNEWS HARDtalk 20240604 23:43:00

richness and in our own genome diversity? we all know that for many people, for many drugs and many vaccines out there, we are, because we are genetically very different, we might respond differently and it would have been fair enough and equitable enough to accelerate some clinical trials in africa to see how the african people respond. ok, so we know that african genomes are the most diverse, as you ve just said, and they re the oldest. there are things in the human genome that we can t study anywhere else but in africa and sub saharan africa is where 70% of all pathogens with pandemic potential emerge. and yet, as we said, only a fraction of global scientific research money goes into africa. so could africa, then, given it s got this rich diversity, become a global leader when it comes to scientific research and finding breakthroughs to cure all sorts of illnesses? absolutely, i believe that africa has what it takes to be a global leader.

Transcripts for BBCNEWS HARDtalk 20240604 15:43:00

in themselves. these vaccines we re talking about, we have evidence we have shared with the african governments, but they don t believe in themselves and they always want help to come from outside. they don t want to invest where their mouth is. if we did the right investment, we shouldn t be in this situation where we are today. we propose accelerating clinical trials for the country, the vaccine that we have, for six months so that at least we could even have a vaccine that has been tried on the continent. the present vaccine that we are having delivered in africa have not gone into any clinical trial on the continent. are we really sure that is very protective against african population, given our own richness and in our own genome diversity? we all know that for many people, for many drugs and many vaccines out there, we are genetically very different. we might respond differently and it would have been fair enough and equitable enough to accelerate some clinical trials in africa t

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