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Transcripts for BBCNEWS BBC News 20211106 18:28:00

a million people without it. they spotted differences in their genes, but interestingly, the differences are similar to those that you might see in someone with anxiety, depression, or insomnia. what that tells us is that these conditions are likely to have a shared genetic origin. they are coming from the same place, effectively, and some of that is hard wired. does that mean basically you could be born with a gene that could either give you ibs or anxiety or both, there s nothing you can do about it? yes, that s absolutely true and that s part of what we ve demonstrated. some people who inherit these genetic variants, they may get ibs, other people may get anxiety, and some people will get both of those conditions. they are sort of hard wired, if you like. ultimately, these findings could lead to new treatments. it gives us a new window on how we think about the management of ibs. a lot of treatments so far have very much focused on the gut and the abdomen and dietary therapies, and

Transcripts for BBCNEWS The Media Show 20211106 16:30:00

of that is hard wired. does that mean basically you could be born with a gene that could either give you ibs or anxiety or both, there s nothing you can do about it? yes, that s absolutely true and that s part of what we ve demonstrated. some people who inherit these genetic variants, they may get ibs, other people may get anxiety, and some people will get both of those conditions. they are sort of hard wired, if you like. ultimately, these findings could lead to new treatments. it gives us a new window on how we think about the management of ibs. a lot of treatments so far have very much focused on the gut and the abdomen and dietary therapies, and those work for some people, but not for everybody. so what our study suggests is that we need to think about more about treatments that affect the interaction between the brain and the gut. and target some of those nervous processes, the neural processes, and that we may well see some benefit there. in your experience, did you feel you were

Transcripts for BBCNEWS BBC News 20211106 20:23:00

in their genes, but interestingly, the differences are similar to those that you might see in someone with anxiety, depression, or insomnia. what that tells us is that these conditions are likely to have a shared genetic origin. they are coming from the same place, effectively, and some of that is hard wired. does that mean basically you could be born with a gene that could either give you ibs or anxiety or both, there s nothing you can do about it? yes, that s absolutely true and that s part of what we ve demonstrated. some people who inherit these genetic variants, they may get ibs, other people may get anxiety, and some people will get both of those conditions. they are sort of hard wired, if you like. ultimately, these findings could lead to new treatments. it gives us a new window on how we think about the management of ibs. a lot of treatments so far have very much focused on the gut and the abdomen and dietary therapies, and those do work for some people, but not for everybody.

Transcripts for BBCNEWS BBC News 20211106 19:20:00

the differences are similar to those that you might see in someone with anxiety, depression, or insomnia. what that tells us is that these conditions are likely to have a shared genetic origin. they are coming from the same place, effectively, and some of that is hard wired. does that mean basically you could be born with a gene that could either give you ibs or anxiety or both, there s nothing you can do about it? yes, that s absolutely true and that s part of what we ve demonstrated. some people who inherit these genetic variants, they may get ibs, other people may get anxiety, and some people will get both of those conditions. they are sort of hard wired, if you like. ultimately, these findings could lead to new treatments. it gives us a new window on how we think about the management of ibs. a lot of treatments so far have very much focused on the gut and the abdomen and dietary therapies, and those do work for some people, but not for everybody. so what our study suggests is that

Transcripts for BBCNEWS BBC News 20211106 16:30:00

they are coming from the same place, effectively, and some of that is hard wired. does that mean basically you could be born with a gene that could either give you ibs or anxiety or both, there s nothing you can do about it? yes, that s absolutely true and that s part of what we ve demonstrated. some people who inherit these genetic variants, they may get ibs, other people may get anxiety, and some people will get both of those conditions. they are sort of hard wired, if you like. ultimately, these findings could lead to new treatments. it gives us a new window on how we think about the management of ibs. a lot of treatments so far have very much focused on the gut and the abdomen and dietary therapies, and those work for some people, but not for everybody. so what our study suggests is that we need to think about more about treatments that affect the interaction between the brain and the gut. and target some of those nervous processes, the neural processes, and that we may well see so

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