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IMAGE: Students at St. Georges Technical High School in Middletown, Delaware are the first high school students in the United States to use the innovative CRISPR in a Box educational gene. view more
Credit: ChristianaCare
St. Georges Technical High School in southern New Castle County, Delaware is the first high school in the United States to use ChristianaCare Gene Editing Institute s innovative CRISPR in a Box Educational Toolkit™ in a science class.
CRISPR in a Box brings to life the much-heralded CRISPR gene editing technology - the genetic scissors that allow scientists to edit DNA. The toolkit is designed for educational sessions in secondary and post-secondary schools and is suitable for remote learning.
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Wilmington, DE, Feb. 11, 2020 -Scientists have developed an affordable, downloadable app that scans for potential unintended mistakes when CRISPR is used to repair mutations that cause disease. The app reveals potentially risky DNA alterations that could impede efforts to safely use CRISPR to correct mutations in conditions like sickle cell disease and cystic fibrosis. The development of the new tool, called DECODR (which stands for Deconvolution of Complex DNA Repair), was reported today in
The CRISPR Journal by researchers from ChristianaCare s Gene Editing Institute.
Our research has shown that when CRISPR is used to repair a gene, it also can introduce a variety of subtle changes to DNA near the site of the repair, said Eric Kmiec, Ph.D., director of ChristianaCare s Gene Editing Institute and the principal author of the study. We developed DECODR to accelerate the development of CRISPR gene therapies by providing a way to rapidly detect these changes so we c
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Gene editing
Gene editing
UD grads find success working at ChristianaCareâs Gene Editing Institute
Natalia Rivera-Torres, Brett Sansbury and Kelly Banas are still in the early stages of their professional careers. But already, these research scientists working at ChristianaCareâs Gene Editing Institute have earned national recognition for their work with CRISPR technology, expanding the use of gene editing to improve the diagnosis and treatment of diseases like cancer while also helping to increase access to gene editing techniques for the next generation of researchers.
Rivera-Torres, who graduated from the University of Delaware in 2019 with a doctorate in medical sciences from the Department of Medical and Molecular Sciences, is credited with helping researchers understand how gene repair is carried out in human cells and also how the process may vary in patient samples. She was also the first graduate student to receive a research fellowship award from the And