Cancer cells may evade chemotherapy by going dormant, suggests study ANI | Updated: Mar 13, 2021 11:24 IST
Washington [US], March 13 (ANI): Cancer cells can dodge chemotherapy by entering a state that bears similarity to certain kinds of senescence, a type of active hibernation that enables them to weather the stress induced by aggressive treatments aimed at destroying them, according to a new study.
The study was led by scientists at Weill Cornell Medicine. These findings have implications for developing new drug combinations that could block senescence and make chemotherapy more effective.
In a study published Jan. 26 in Cancer Discovery, a journal of the American Association for Cancer Research, the investigators reported that this biologic process could help explain why cancers so often recur after treatment. The research was done in both organoids and mouse models made from patients samples of acute myeloid leukaemia (AML) tumours. T
Study finds cancer cells may evade chemotherapy by going dormant eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.
March 2, 2021
The Office of Academic Integration (OVPAI) has awarded $750,000 in seed grants to 10 studies ranging from refugee health and legal rights, to a vaccine treating fentanyl addiction and overdose, to pancreatic cancer and antibiotic tolerance.
This year’s awardees represent faculty collaborations across five colleges and schools, and 18 departments and divisions across the Cornell Ithaca campus and Weill Cornell Medicine and Cornell Tech in New York City.
Designed to catalyze collaborative research interactions among Cornell faculty based in Ithaca and New York City, OVPAI provides funding opportunities that foster transdisciplinary, multi-investigator programs that aim to be competitive for support from federal funders and major foundations.
Date Time
Gene critical to immune cell development identified
Much of the three-dimensional architecture of the genome in antibody-producing immune cells is dependent on a gene called SMC3. When this gene is not working properly it can lead to improper immune cell development and to cancer, by disrupting how DNA is structured inside the cell nucleus, according to a team of researchers from Weill Cornell Medicine. Victoria Béguelin/Provided
The two canvases represent the genome as folded in cells with normal (left) or reduced levels of SMC3. The normal canvas is highly structured and functional, while the other canvas has lost its pattern and has open threads.
Scientists discover a key genetic driver of lymphomas medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.