Tumors are composed of rapidly multiplying cancer cells. Understanding which biochemical processes fuel their relentless growth can provide hints at therapeutic targets.
New spatial tools measure how fast nutrients in tumors flow through different pathways, identifying pathways whose activities are uniquely elevated in brain cancer and offering clues for potential treatment strategies.
Researchers led by Gary J. Patti in Arts & Sciences at Washington University in St. Louis established a method to watch what nutrients are used at which rates spatially throughout a tumor. The new approach offers clues for potential treatment strategies.