Agent 47 has left behind his life as an assassin and retreated to a church in Sicily to seek peace, working as a gardener for Father Vittorio, his best friend and mentor. After Vittorio is kidnapped, 47 decides to go back to his old job.
As Agent 47, a bald test subject branded with a barcode tattooed on the back of his head and who is rigorously trained in methods of murder, assassinate wealthy and decadent criminals.