Manuel Romero-Gómez and colleagues discuss how diet and modifiable factors can help prevent of non-alcoholic fatty liver disease and the importance of engaging all society through awareness, education, and policy change
### Key messages
Non-alcoholic fatty liver disease (NAFLD) is characterised by fat accumulation in hepatocytes in people who drink little or no alcohol and is strongly related to metabolic disorders like obesity, type 2 diabetes, dyslipidaemia, and arterial hypertension.1 The global prevalence of NAFLD has increased over time, now reaching more than 30% of the general adult population, with an estimated annual growth of 0.7%.2 NAFLD is a complex, heterogeneous, and dynamic disease, and progression to fibrosis (scarring of the liver) occurs in around 10-15% of patients with NAFLD.3 NAFLD is one of the main risk factors for developing liver cancer, which represents the third highest cause of death by cancer in the latest Globocan report.4
People with obesity are 3.5 t
Data indicate that the pancreas as a target of SARS-CoV-2 infection and suggest that pancreatic beta cell involvement could contribute to the metabolic dysregulation seen in patients with COVID-19.