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French researchers prepare for HIV vaccine trials, using dendritic cells

French researchers prepare for HIV vaccine trials, using dendritic cells By RFI © Credit: NIAID. License: CC BY 2.0. In a world first for vaccines, researchers at France s Vaccine Research Institute have targeted essential cells for combating HIV/Aids with dendritic cells, the so-called sentinels of our immune system. Clinical trials are set to begin within weeks.  This is how it works: The vaccine is launched directly at the cells, delivery as a kind of rocket, producing antibodies which attach themselves to fragments of HIV, France Info reported on Friday. “Firstly, we target the good cells, then we go after the pieces of virus, in this case the envelope of HIV which allows it to enter the body,” explains Prof Yves Levy, director for this project.

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